Posted on: 20/06/2025

MTPConnect’s TTRA Program Invests $12M to Support Homegrown Heart Disease and Diabetes Innovations

MTPConnect has announced it is injecting $12.07 million to back 14 homegrown life science companies developing new medical devices and drugs that aim to reduce the burden of cardiovascular disease and complications of diabetes (type 1 and type 2) for patients, carers, families and communities.

The funding comes from MTPConnect’s Targeted Translation Research Accelerator (TTRA) Drugs and Devices program, an initiative of the Medical Research Future Fund.

The announcement was made in parallel at the BIO International Convention in Boston, one of the world’s biggest biotech events bringing together sector leaders from Australia and around the world.

MTPConnect CEO Stuart Dignam said this funding injection is critical to backing Australian innovations to tackle these significant chronic health problems and scale in our backyard rather than offshore.

“Access to funding remains the biggest challenge for start-ups and innovators. The capital markets, especially when you’re at an early stage with your innovation, are particularly tough – and now they have heightened global business uncertainty and tariff turmoil to contend with,” Mr Dignam said.

“Following an open and rigorous assessment process, we’re backing established SMEs, start-ups and spin-outs in New South Wales, South Australia, Tasmania, Victoria and Western Australia.

“These 14 new projects have attracted more than $17 million in additional contributions from the awarded companies and their partners.

“MTPConnect’s investment, combined with the matching industry contributions, represents a near $30 million downpayment on the future of Australia’s brilliant life science innovators.

“We’re particularly pleased that 50 per cent of the funded SMEs are organisations led by women which is well above the representation of women in senior management (26%) or CEO roles (10%) within STEM industries in Australia, according to Stem Equity Monitor 2024.

“In addition to vital funding, these 14 companies will receive ongoing acceleration support through mentoring and access to specialist advice from MTPConnect, and guidance from our industry impact partners, CSL and Roche Diagnostics so they can tap into the best of global industry expertise.

“MTPConnect’s tried and tested accelerator model has shown that pairing non-dilutive funding with access to industry knowledge, mentoring, market expertise and commercialisation skills is a powerful multiplier for start-ups and SMEs that truly boosts their chances of success.”

“We’ll be working with these companies over the next few years and making additional funding available on a competitive basis for those hitting their commercialisation milestones.

“We want to see these homegrown innovations scale in Australia first rather than offshore and drive sovereign success which will power local job creation and improve health outcomes for Australians and others around the world,” Mr Dignam said.

A summary of companies awarded funding are listed below:

TTRA Drugs Investment Outcomes
(in alphabetical order)

Anaxis Pharma Pty Ltd, Victoria, $333,236 Tranche A investment

Breaking the cycle: targeting cell death in diabetic kidney disease

Argenica Therapeutics Limited, Western Australia, $1,000,000 Tranche A investment

Phase 2b/3 adaptive trial to determine the safety and efficacy of ARG-007 in reducing disability in acute ischaemic stroke patients

Aspecthera Pty Ltd, Tasmania, $500,000 Tranche A investment

Novel eye-drop therapy for mild, moderate and severe non-proliferative diabetic retinopathy to prevent vision loss and disease progression

Atherid Therapeutics Pty Ltd, Western Australia, $750,000 Tranche A investment

Establishing GMP production of a biologic therapeutic for treating patients with atherosclerotic cardiovascular disease

Endo Axiom Pty Ltd, New South Wales, $1,079,424 Tranche A investment

Beyond the needle: Evaluating a safe and smart oral insulin in type 1 diabetes

Inosi Therapeutics Pty Ltd, Victoria, $968,192.63 Tranche A investment

Development of an IRAP inhibitor for the treatment of diabetic kidney disease

Nanomedx Pty Ltd, New South Wales, $750,000 Tranche A investment

Local regulation of inflammation for the treatment of peripheral arterial disease

ProGenis Pharmaceuticals Pty Ltd, Western Australia, $369,706 Tranche A investment

PGP-011 as an effective RNA therapeutic for improving insulin sensitivity

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TTRA Devices Investment Outcomes
(in alphabetical order)

CathRx Ltd, New South Wales, $1,100,000 Tranche A investment

ElectroPulse pulsed field ablation system to treat AF (ELECTROPULSE AF)

I D & E Pty Ltd, New South Wales, $1,200,000 Tranche A investment

Ocular drug delivery system

Theia Medical Pty Ltd, South Australia, $1,000,000 Tranche A investment

Hybrid 3D-printed intravascular imaging device for accurate detection of high-risk coronary artery disease

Venstra Medical Pty Ltd, New South Wales, $1,000,000 Tranche A investment

The world’s lowest profile most powerful temporary heart pump to save the lives of patients in cardiogenic shock

Wavewise Analytics Pty Ltd (formerly Cyban), Victoria, $996,995 Tranche A investment

Clinical and product development of Wavewise Analytics’ ARGUS stroke monitoring and detection system: Real-time continuous non-invasive blood flow monitoring

ZiP Diagnostics Pty Ltd, Victoria, $1,019,134 Tranche A investment

Development of a low-cost, rapid, point-of-care lateral flow test for prediction and early diagnosis of preeclampsia

MTPConnect acknowledges the traditional custodians of Australia. We pay our respects to elders past, present and future, of all Aboriginal and Torres Strait Islander nations.

WALSIH MTPConnect SA