This second edition of the Pulse Report examines the current and future workforce requirements in the emerging complex therapeutics manufacturing sector. With findings derived from an extensive survey of key Australian employers investing in this sector, the report reveals there is considerable work to be done if Australia is to deliver on its substantial investments in this critical sovereign manufacturing capability. The challenge remains to ensure growing and scaling medical science SMEs can access the skilled staff they need, here in Australia, to get their products to market and ultimately to patients.